The Discovery of IgE

Publication date: Available online 23 April 2016
Source:Journal of Allergy and Clinical Immunology
Author(s): S.G.O. Johansson
In 1919 the search in serum of allergic individuals for the factor, later called reagin,that could mediate an allergy, e.g. allergic asthma. In 1967 the fifth class of immunoglobulins, IgE, was discovered and found to be able to carry regain activity. The discovery has had an immense importance for understanding, diagnosis and treatment of allergic diseases.

Teaser

The discovery of IgE, its physico-chemical and immunological characterization and the understanding of its key-role in allergic inflammation, have been of immense importance for the specialty allergology and have had a significant impact on diagnosis and treatment of allergy.


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