Persistent nodal histoplasmosis in NF-κB essential modulator (NEMO) deficiency: Report of a case and review of infection in primary immunodeficiencies

Publication date: Available online 24 April 2016
Source:Journal of Allergy and Clinical Immunology
Author(s): Jana P. Lovell, Ladan Foruraghi, Alexandra F. Freeman, Gulbu Uzel, Christa S. Zerbe, Helen Su, Amy P. Hsu, Steven M. Holland
In the absence of acquired or secondary immunosuppression, mutations causing failure to properly activate the IL-12/IFN-γ pathway, NF-κB, or STAT3 should be excluded in patients presenting with severe histoplasmosis.



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