50 lat IgE

Publication date: Available online 16 April 2016
Source:Alergologia Polska - Polish Journal of Allergology
Author(s): Robert Kruszewski, Jerzy Kruszewski
The discovery of IgE was a major breakthrough in the development of allergology as a medical discipline. Exactly fifty years ago two independent research teams in USA and Sweden investigated and explained the role of unknown factor called reagin in allergic hypersensitivity. Provided evidence suggested that reagins are immunoglobulins of a new class. Further research of IgE properties significantly improved our understanding of the mechanism of allergic reaction. Current diagnostic and therapy of allergic diseases are largely based on these findings.



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