Chronic respiratory failure due to toxic epidermal necrosis in a 10 year old girl.

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Chronic respiratory failure due to toxic epidermal necrosis in a 10 year old girl.

Acta Clin Belg. 2015 Feb;70(1):69-71

Authors: Thimmesch M, Gilbert A, Tuerlinckx D, Bodart E

Abstract
Toxic epidermal necrosis is a severe mucocutaneous disease with a high mortality rate. A third of the patients surviving the acute phase will develop pulmonary complications. The most frequent complication is bronchiolitis obliterans. Despite well-conducted treatment, in most cases, lung injury often leads to chronic respiratory failure. We describe here the case of a young patient that presented a toxic epidermal necrosis at the age of 3 years. Poor therapeutic compliance result in chronic respiratory failure and after 7 years of follow-up, pulmonary transplant remains the only long-term alternative. Close monitoring of respiratory symptoms in the course of toxic epidermal necrosis, intense treatment as soon as they appear and a long-term follow-up are essential to postpone chronic respiratory failure.

PMID: 25324191 [PubMed - indexed for MEDLINE]

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