Metabolic and epigenomic reprogram cooperatively creates phenotypic differences of senescent cells, which may provide new clues to control aging processes

Cellular Senescence Variation by Metabolic and Epigenomic Remodeling.:

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Cellular Senescence Variation by Metabolic and Epigenomic Remodeling.

Trends Cell Biol. 2020 Sep 23;:

Authors: Nakao M, Tanaka H, Koga T

Abstract

Cellular senescence is a state of permanent cell cycle arrest accompanied by unique secretory actions, which influences tissue formation, tumor suppression and aging in vivo. Recent evidences suggest that metabolic and epigenomic reprogram cooperatively creates phenotypic differences of senescent cells, which may provide new clues to control aging processes.



PMID: 32978041 [PubMed - as supplied by publisher]