Abstract The applicants Syngenta Crop Protection, UPL Europe Ltd. and Oxon Italia S.p.A. submitted requests to the competent national authority in the Netherlands to evaluate the confirmatory data for chlorothalonil that were identified in the framework of the MRL review under Article 12 of Regulation (EC) No 396/2005 as not available; in addition, Syngenta and UPL submitted requests for modifications of existing MRLs. Considering the recent decision on the non‐approval of chlorothalonil, the requests...
Mon Sep 28, 2020 12:21
Related Articles The co-occurrence of a four-headed coracobrachialis muscle, split coracoid process and tunnel for the median and musculocutaneous nerves: the potential clinical relevance of a very rare variation. Surg Radiol Anat. 2020 Sep 26;: Authors: Olewnik Ł, Zielinska N, Karauda P, Duparc F, Georgiev GP, Polguj M Abstract The coracobrachialis muscle (CBM) originates from the apex of the coracoid process, in common with the short head...
Mon Sep 28, 2020 15:03
Abstract Genital lymphedema is a rare condition in males that can lead to difficulty in voiding, sexual function, hygiene, and mobility. Only several methods of treatment have been developed and studied, primarily focusing on restoring patency of diseased lymph channels or resection of affected tissue. We are the first to describe the surgical technique and our experience of using free submental and submandibular arterio‐venous vascularized lymph node transfer specifically for the treatment of scrotal...
Mon Sep 28, 2020 14:56
Journal of the American Chemical SocietyDOI: 10.1021/jacs.0c07367
Fri Sep 25, 2020 07:00
Journal of the American Chemical SocietyDOI: 10.1021/jacs.0c06820
Fri Sep 25, 2020 07:00
Journal of the American Chemical SocietyDOI: 10.1021/jacs.0c06942
Sun Sep 27, 2020 07:00
Technology in Cancer Research &Treatment, Volume 19, Issue , January-December 2020. Tissue electrolysis is an alternative modality that uses a low intensity direct electric current passing through at least 2 electrodes within the tissue and resulting electrochemical products including chlorine and hydrogen. These products induce changes in pH around electrodes and cause dehydration resulting from electroosmotic pressure, leading to changes in microenvironment and thus metabolism of the tissues,...
Mon Sep 28, 2020 12:28
Technology in Cancer Research &Treatment, Volume 19, Issue , January-December 2020. Objective:This study aimed to assess protein kinase D1 expression and its association with tumor characteristics as well as prognosis in patients with non-small cell lung cancer.Methods:Protein kinase D1 expression in tumor tissues and adjacent tissues from 172 patients with non-small cell lung cancer who underwent surgical resection were analyzed by immunohistochemical staining. Based on the total immunohistochemical...
Mon Sep 28, 2020 12:29
Abstract Background Imaging is crucial for assessing the severity and progression of COVID-19. Radiographers are amongst the first-line health professionals that may be exposed to infected persons. This work describes the early experience of radiographers in Ireland to the impact of COVID-19 using two electronic surveys distributed 6 weeks apart. Results were analysed using descriptive statistics and thematic analysis. ...
Fri Sep 25, 2020 03:00
Abstract Desmoid tumors (DTs) are a rare and biologically heterogeneous group of locally aggressive fibroblastic neoplasm: their biological behavior spectrum ranges from indolent to aggressive tumors. DTs are classified as intra-abdominal, extra-abdominal, and within the abdominal wall lesions. It is well known that abdominal and extra-abdominal DTs are associated with familial adenomatous polyposis (FAP) and Gardner syndrome. Possible risk factors are...
Fri Sep 25, 2020 03:00
Related Articles Impacts of Type 2 Diabetes on Disease Severity, Therapeutic Effect, and Mortality of Patients With COVID-19. J Clin Endocrinol Metab. 2020 Dec 01;105(12): Authors: Wang X, Liu Z, Li J, Zhang J, Tian S, Lu S, Qi M, Ma J, Qiu B, Dong W, Xu Y Abstract PURPOSE: Coronavirus disease 2019 (COVID-19) has become a topic of concern worldwide; however, the impacts of type 2 diabetes mellitus (T2DM) on disease severity, therapeutic effect,...
Mon Sep 28, 2020 15:34
Abstract Forgetfulness is a common complaint of pregnant women, who also often report impaired nocturnal sleep. Considering sleep's well‐known beneficial role in consolidating newly encoded memory content, we hypothesized that pregnant women would display detrimental changes in objective sleep measures and associated memory deficits. We compared the consolidation of declarative as well as procedural memory across sleep in 21 healthy, third‐trimester pregnant women versus 20 matched non‐pregnant...
Mon Sep 28, 2020 15:00
Related Articles The effect of noise exposure on the vestibular systems of dental technicians. Noise Health. 2019 Nov-Dec;21(103):223-231 Authors: Alqudah S Abstract Background: Noise exposure is the primary cause of acquired hearing loss in several occupational settings, including dental laboratories and clinics. However, the impact of noise exposure on the vestibular system is not as well researched. Purpose: To investigate...
Mon Sep 28, 2020 15:38
Carcinoma of unknown primary (CUP) syndrome occurs when metastases from an unknown primary site spread to multiple organs. Occult breast cancer (OBC) is defined as a clinically recognizable metastatic carcinoma from an undetectable primary breast tumor. It accounts for 0.3–1% of all breast cancers, often presenting with lymph node, bone, and skin metastases. Clinical and radiological examinations represent the first steps in the diagnostic algorithm for CUP syndrome from OBC. However, histological...
Mon Sep 28, 2020 14:37
Splenic metastasis is known to occur at the terminal stage of cancer. While peritoneal dissemination is the most frequent recurrence of gastric cancer, metastasis to the spleen from gastric cancer is very rare. Splenectomy is currently the most effective probable treatment for solitary splenic metastasis of gastric cancer; it provides a good patient prognosis. However, careful consideration of surgical indications is required, as splenic metastasis is typically accompanied by multi-organ metastasis...
Mon Sep 28, 2020 14:38
Ogilvie syndrome or intestinal pseudo-obstruction is a clinical syndrome characterized by autonomic imbalance affecting peristalsis of colon leading to obstructive signs and symptoms. The etiologies commonly implicated are drugs affecting the cholinergic system, narcotics, electrolyte imbalance, severe sepsis, cancer, major surgery, and renal and cardiac failure. Ogilvie syndrome secondary to chemotherapy is a very rare phenomenon with very few reports in the literature. Cisplatin-induced neuropathy...
Mon Sep 28, 2020 14:38
We report a case of long-standing ulcerative colitis with intramucosal well- and poorly differentiated adenocarcinomas detected over a 6-month duration. A Japanese man in his sixties with a 31-year history of ulcerative colitis had a 1.1-cm-sized intramucosal well-differentiated tubular adenocarcinoma in the rectum resected by endoscopic submucosal dissection. At the follow-up colonoscopy, a biopsy near the endoscopic submucosal dissection scar revealed poorly differentiated adenocarcinoma, and a...
Mon Sep 28, 2020 14:38
Abstract The sharp distinction between biological traits and culturally based traits, which had long been standard in evolutionary approaches to behavior, was blurred in the early 1980s by mathematical models that allowed a co‐dependent evolution of genetic transmission and cultural information. Niche‐construction theory has since added another contrast to standard evolutionary theory, in that it views niche construction as a cause of evolutionary change rather than simply a product of selection....
Mon Sep 28, 2020 15:46
Fibrous dysplasia (FD) can be surgically managed by bone shaving, however it is best done using navigational surgery to achieve symmetry and adequate removal of FD bone.1 Unfortunately, in certain centres, navigational surgery is still not available. A patient was referred for management of excess FD bone over the right frontal region extending laterally to the frontozygomatic suture region causing facial asymmetry (Fig. 1). We have successfully used a hybrid technique to ensure three dimensional...
Mon Sep 28, 2020 03:00
Related Articles Betahistine add-on therapy for treatment of subjects with posterior benign paroxysmal positional vertigo: a randomized controlled trial. Braz J Otorhinolaryngol. 2020 Sep 12;: Authors: Sayin I, Koç RH, Temirbekov D, Gunes S, Cirak M, Yazici ZM Abstract INTRODUCTION: Benign paroxysmal positional vertigo is a common vestibular disorder that accounts for one fifth of hospital admissions due to vertigo, although it is commonly undiagnosed....
Mon Sep 28, 2020 16:11
Related Articles Olfactory impairment and the risk of cognitive decline and dementia in older adults: a meta-analysis. Braz J Otorhinolaryngol. 2020 Sep 12;: Authors: Chen Z, Xie H, Yao L, Wei Y Abstract INTRODUCTION: The prediction of the impact of olfactory impairment on cognitive decline in older adults has been different among different age groups. OBJECTIVE: This meta-analysis sought to estimate the predictive power of olfactory...
Mon Sep 28, 2020 16:11
Related Articles Evaluation of postoperative satisfaction with rhinoseptoplasty in patients with symptoms of body dysmorphic disorder. Braz J Otorhinolaryngol. 2020 Sep 12;: Authors: Rabaioli L, Oppermann PO, Pilati NP, Klein CFG, Bernardi BL, Migliavacca R, Lavinsky-Wolff M Abstract INTRODUCTION: The prevalence of body dysmorphic disorder among candidates for plastic surgery may vary from 6% to 54%. Some studies report discrete benefits with...
Mon Sep 28, 2020 16:11
Introduction: Male genitalia are thought to ensure transfer of sperm through direct physical contact with female during copulation. However, little attention has been given to their pre-copulatory role with respect to sexual selection and sexual conflict. Males of the fruitfly Drosophila pachea have a pair of asymmetric external genital lobes, which are primary sexual structures and stabilize the copulatory complex of female and male genitalia. Results: We tested for a pre-copulatory role of these...
Mon Sep 28, 2020 03:00
Abstract The crisis of replication has led many to blame statistical significance tests for making it too easy to find impressive looking effects that do not replicate. However, the very fact it becomes difficult to replicate effects when features of the tests are tied down actually serves to vindicate statistical significance tests. While statistical significance tests, used correctly, serve to bound the probabilities of erroneous interpretations of data, this error control is...
Mon Sep 28, 2020 03:00
Objective Determine the effect of patient demographics and surgical approach on patient outcomes after tracheal resection in the management of thyroid cancer. Study Design Systematic review and meta‐analysis. Methods Systematic review of literature was performed using PubMed, Embase, and Cochrane Library to identify patients with thyroid carcinoma who underwent tracheal resection. Pooled estimates for patient demographics, presenting findings, complications, and outcomes are determined...
Mon Sep 28, 2020 14:28
Mon Sep 28, 2020 12:29
Mon Sep 28, 2020 12:29
Mon Sep 28, 2020 12:29
Zusammenfassung Die adulte Form der Dermatomyositis (DM) wird mit einer Prävalenz von 6–7 auf 100 000 Einwohner pro Jahr angegeben. Auf Grund der nachweislich steigenden Inzidenz, der häufig unterschätzen Systembeteiligung und neuer Entwicklungen zu den Myositis‐spezifischen Antikörpern (MSA) wurde diese kompakte Übersicht zur Dermatomyositis erarbeitet. Des Weiteren wird das klinische Spektrum nicht nur dermatologischer Parameter, sondern auch organischer Symptome erläutert. Die diagnostische...
Mon Sep 28, 2020 12:29
Summary Dermatomyositis (DM) in adults has a prevalence of 6–7 per 100,000 population per year. This dedicated compact overview was prepared due to an increasing incidence as well as an often underestimated systemic involvement and new developments in myositis‐specific antibodies (MSA). The spectrum of clinical dermatological and systemic symptoms is described. Related diagnostic procedures are depicted, and therapeutic regimens based on the German S2k guidelines and the current literature are presented....
Mon Sep 28, 2020 12:29
Zusammenfassung Die optische Kohärenztomographie (OCT) ist ein nichtinvasives, hochauflösendes Bildgebungsverfahren, das in der Dermatologie zunehmend an Bedeutung gewinnt. Das Prinzip der OCT ist mit dem der Sonographie vergleichbar, bei dem statt Ultraschallwellen allerdings Infrarotlaserstrahlung verwendet wird. Klinisch eignet sich die OCT nachweislich zur Unterscheidung verschiedener nichtmelanozytärer Hautkrebsarten in einem frühen Erkrankungsstadium. Bei der optischen Kohärenztomographie...
Mon Sep 28, 2020 12:29
Zusammenfassung Hintergrund und Zielsetzung Ziel dieser Arbeit war die Konzeptionierung und Evaluation einer neuartigen interprofessionellen Lehrveranstaltung zum Thema Wundmanagement. Methoden Nach einer Überprüfung der Ist‐Situation mittels Befragung von Studierenden der Humanmedizin in der Hauptvorlesung Dermatologie wurde ein 150 Minuten umfassendes Lehrkonzept mit praktischen Inhalten zum Thema Wundmanagement erstellt und innerhalb der bereits etablierten studentischen Übungseinrichtung...
Mon Sep 28, 2020 12:29
Zusammenfassung Hintergrund und Ziele Infantile Hämangiome können sowohl durch systemische Propranolol‐ als auch durch Neodym:YAG‐Farbstofflaser‐Kombinationstherapie erfolgreich behandelt werden. In dieser retrospektiven Studie wurden Wirksamkeit und Sicherheit der sequenziellen und parallelen Therapie komplizierter Hämangiome, die mit beiden Verfahren behandelt wurden, evaluiert. Patienten und Methoden 30 Kinder mit 48 komplizierten Hämangiomen wurden mit Propranolol‐ und Neodym: YAG‐Farbstofflaser‐Kombinationstherapie...
Mon Sep 28, 2020 12:29
Zusammenfassung Die Dyskeratosis congenita ist eine seltene Erbkrankheit, die hauptsächlich Männer betrifft und klinisch durch die klassische Trias retikuläre Hyperpigmentierung, Onychodystrophie und Leukoplakie gekennzeichnet ist. Sie erhöht das Risiko für maligne Erkrankungen und andere potenziell zum Tod führende Komplikationen wie Knochenmarksversagen, Lungen‐ und Lebererkrankungen. Mutationen in 19 Genen wurden mit der Dyskeratosis congenita assoziiert. Circa ein Fünftel der pathogenen Mutationen...
Mon Sep 28, 2020 12:29
Zusammenfassung Hintergrund und Ziel Pigmentierte intraepidermale Karzinome sind dermatoskopisch durch Punkte und strukturlose Bereiche sowie durch linear angeordnete Punkte und Knäuelgefäße gekennzeichnet. Es gibt keine Studien zu den dermatoskopischen Merkmalen pigmentierter intraepidermaler Karzinome an Kopf und Hals. Unser Ziel ist die Beschreibung des klinischen und dermatoskopischen Erscheinungsbildes dieser Entität. Patienten und Methodik Wir analysierten retrospektiv 79 Fälle...
Mon Sep 28, 2020 12:29
Summary Background In the clinical treatment pathways of certified oncological centers, psychotherapeutic services are mandatory. Although patients with somatic, non‐oncological illnesses show an equally high prevalence of psychosocial stress, these guidelines do not exist for the general hospital sector. Are these patients really less burdened and is psychological support only needed in individual cases? The example of dermatological patients will be used to show whether the need for psychosocial...
Mon Sep 28, 2020 16:36
Abstract The aim of this study was to evaluate the skin problems and dermatological life quality of the health care workers (HCWs) due to personal protection equipment (PPE) use, who are at high risk for Covid‐19 infection. A questionnaire about HCWs' PPE use, their skin symptoms, and prevention, management methods and Dermatology Life Quality Index (DLQI) was fulfilled. The median age of 440 participants was 33.5 (21.0‐65.0) years old. Skin problems were found to be 90.2%, the most common were...
Mon Sep 28, 2020 13:49
Background Supplemental breast cancer screening with breast magnetic resonance imaging (MRI) is recommended for women at high risk of breast cancer. To the authors' knowledge, recent national trends in breast MRI use are unknown. Methods The authors used claims data from a large national insurer to calculate screening breast MRI rates from 2006 to 2016 in a US cohort of 10 million women aged 20 to 64 years. Use was stratified by subgroups of women with a BRCA mutation, family history of breast...
Mon Sep 28, 2020 15:24
Background Individuals of advanced age with comorbidities face a higher risk of death from coronavirus disease 2019 (COVID‐19), especially once they are ventilator‐dependent. Respiratory decline in patients with COVID‐19 is precipitated by a lung‐mediated aberrant immune cytokine storm. Low‐dose lung radiation was used to treat pneumonia in the pre‐antibiotic era. Radiation immunomodulatory effects may improve outcomes for select patients with COVID‐19. Methods A single‐institution trial evaluating...
Mon Sep 28, 2020 15:31
Cancer Biotherapy and Radiopharmaceuticals, Ahead of Print.
Thu Sep 24, 2020 10:00
The article proposes an image classification with four types according to the relationship between a tumor and the splenic vein. We establish a scoring system by combining two parameters (that are the image classification and tumor size), which are helpful in making a spleen‐preservation strategy during laparoscopic spleen preserving distal pancreatectomy. Abstract Background A reasonable surgical plan is crucial to laparoscopic spleen‐preserving distal pancreatectomy. This study proposed...
Mon Sep 28, 2020 14:34
Biliary complications are common in donation after circulatory death liver transplantation. A risk factor analysis was performed to identify features associated with biliary complications in this population within an Australian setting. Abstract Background Biliary complications are the most common complications of donation after circulatory death (DCD) liver transplantation and the international experience with DCD transplants suggests increased rates of biliary complications compared...
Mon Sep 28, 2020 14:36
Stem Cells and Development, Ahead of Print.
Thu Sep 24, 2020 10:00
Conditions: Gastrointestinal Cancer; Breast Cancer; Head and Neck CancerIntervention: Other: Pharmacogenomics (PGx) Testing and Genomics Prescribing Information (GPS)Sponsor: University of ChicagoNot yet recruiting
Wed Sep 09, 2020 19:00
Condition: Oropharynx CancerIntervention: Diagnostic Test: Examination of salivaSponsor: Aalborg University HospitalRecruiting
Mon Sep 28, 2020 18:01
Conditions: Head Neck Cancer; Esophageal Cancer; GastrostomyIntervention: Diagnostic Test: blue laser imagingSponsor: Georg DultzRecruiting
Mon Sep 28, 2020 18:01
Condition: Head and Neck Squamous Cell CarcinomaIntervention: Diagnostic Test: Blood sampleSponsor: Aalborg University HospitalRecruiting
Mon Sep 28, 2020 18:01
Expanded Access to Ulixertinib (BVD-523) in Patients With Advanced MAPK Pathway-Altered Malignancies
Conditions: Pancreatic Cancer; Small Bowel Cancer; Colorectal Cancer; Melanoma; Non Small Cell Lung Cancer; Thyroid Cancer; Bladder Cancer; Head and Neck Cancer; Gastric Cancer; Esophageal Cancer; Cholangiocarcinoma; Ovarian Cancer; Hepatocellular Carcinoma; Glioblastoma; MAPK Gene Mutation; KRAS Activating Mutation; BRAF Gene Mutation; NRAS Gene Mutation; HRAS Gene Mutation; MEK Mutation; ERK MutationIntervention: Drug: Ulixertinib (BVD-523)Sponsors:...
Mon Sep 28, 2020 18:01
Abstract We aimed to determine the pathogenesis of gastric mixed adenoneuroendocrine carcinoma (MANEC) and pure neuroendocrine carcinoma (NEC) which is largely unknown. Targeted DNA sequencing was performed on 34 tumor samples from 21 patients – 13 adenocarcinoma (ADC)/NEC components from MANECs and eight pure NECs – and 21 matched non‐neoplastic gastric tissue. Mutational profiles of MANEC/NEC were compared with those of other tumors using public databases. The majority (64.1%; 59/92) of mutations...
Mon Sep 28, 2020 15:04
Journal of Adolescent and Young Adult Oncology, Ahead of Print.
Thu Sep 24, 2020 10:00
Chronic Respiratory Disease, Volume 17, Issue , January-December 2020. Elderly patients awaiting lung resection surgery often have poor physical function, which puts them at a high risk of postoperative pulmonary complications. The aim of this study was to investigate the impact of preoperative physical performance on postoperative pulmonary complications in patients awaiting lung resection surgery. In this prospective multicenter cohort study, the characteristics of patients and postoperative pulmonary...
Mon Sep 28, 2020 14:24
Tissue Engineering Part A, Ahead of Print.
Fri Sep 25, 2020 10:00
ABSTRACT Obesity is a worldwide issue that many global health authorities consider a growing epidemic. Having a positive correlation between increases in the industrialization of processed foods and sedentary occupations as well as a lack of access to healthcare in poorer socioeconomic areas, obesity is a multifactorial disease affecting several organ systems. The tendency for obesity to cause detrimental changes to the human body is a focal point for healthcare providers to establish more effective...
Mon Sep 28, 2020 18:45
Abstract Introduction Congenital tracheal anomalies are associated with high morbidity and mortality. The etiology of congenital tracheal anomalies is not well understood, but often attributed to malformed tracheal cartilage. The development of tracheal cartilage has not been described in detail. In this study we aimed to investigate the development pattern and timing of normal tracheal cartilage to better understand the etiology of tracheal anomalies. Materials and Methods The development...
Mon Sep 28, 2020 18:46
Abstract Introduction Understanding the contribution of the fibularis longus tendon to the support of the midfoot arches has potential therapeutic applications. This cadaveric study sought to quantify this support across both the transverse arch and medial longitudinal arch and to establish whether a correlation exists between this support and the angle at which the tendon enters the sole. Materials and Methods Markers placed in 11 dissected cadaveric foot specimens defined the arch boundaries....
Mon Sep 28, 2020 18:47
Abstract The conclusions of the EFSA following the peer review of the initial risk assessment carried out by the competent authority of the rapporteur Member State, the United Kingdom, for the pesticide active substance tri‐allate are reported. The context of the peer review was that requested by the European Commission following the submission and evaluation of confirmatory data. The conclusions were reached on the basis of the evaluation of the representative uses of tri‐allate as a herbicide...
Mon Sep 28, 2020 12:24
Abstract In accordance with Article 6 of Regulation (EC) No 396/2005, the applicant Corteva submitted a request to the competent national authority in Italy to modify the existing maximum residue levels (MRLs) for the active substance penthiopyrad in Florence fennels and celeries. The data submitted in support of the request were found to be sufficient to derive MRL proposals for Florence fennels and celeries. Adequate analytical methods for enforcement are available to control the residues of penthiopyrad...
Mon Sep 28, 2020 12:26
Abstract Introduction Intracranial meningiomas rarely present with multiple lesions. To the best of our knowledge, current literature regarding meningiomatosis (MM) is mostly comprised of small case series and individual reports. Hence, survival outcome data are limited. The Objective of this study is to explore the influence of sex, age, and number of lesions on overall survival (OS) in patients with MM. ...
Mon Sep 28, 2020 03:00
Dental hygienist training at the UW School of Dentistry is expanding significantly, thanks to a new partnership between the school and Seattle’s Shoreline Community College. This year, 10 Shoreline students in the second year of their school’s accredited two-year program are training at the School of Dentistry before receiving their Dental Hygiene Associate of Applied Sciences degree. The post Shoreline CC is school’s new dental hygiene training partner appeared first on UW School of Dentistry.
Mon Sep 28, 2020 18:27
Arterial tortuosity is a widespread condition commonly occurring in cerebral arteries and often associated with the elderly. Moderate arterial tortuosity is often not symptomatic, but if there is severe tortuo...
Mon Sep 28, 2020 03:00
Journal of the American Chemical SocietyDOI: 10.1021/jacs.0c06916
Mon Sep 28, 2020 07:00
Journal of the American Chemical SocietyDOI: 10.1021/jacs.0c09572
Mon Sep 28, 2020 07:00
Journal of the American Chemical SocietyDOI: 10.1021/jacs.0c08510
Mon Sep 28, 2020 07:00
Abstract The lack of diversity in the archaeological community is worsened by the sense of exclusivity created at the meeting of archaeological practice and descendant communities. The authors’ work, carried out in partnership with Indo-Hispano/a communities in New Mexico, attempts to counteract this steep gradient of inclusion through the incorporation, professionalization, and leadership of our research collaborators. Our work confronts historical paradigms denying the significance...
Mon Sep 28, 2020 03:00
Researchers have uncovered a new parvovirus strategy for reaching the cell nucleus which is their site of replication. This new method of entry is a good example of host-driven evolution.
Thu Sep 24, 2020 15:27
Nivolumab, a fully human IgG4 immune checkpoint inhibitor (ICI) antibody, has been approved for a variety of cancers. Several endocrine-associated immune-related adverse events have been reported, but the incidence rate is relatively low. This is a case of a patient with gastric cancer who underwent nivolumab therapy, leading to type 1 diabetes as well as adrenocorticotropic hormone (ACTH) deficiency and hypothyroidism almost simultaneously. A 70-year-old man with no previous history of diabetes...
Mon Sep 28, 2020 15:53
Abstract Purpose To evaluate the serum level of zonulin, which is an intestinal permeability (IP) biomarker, in primary hyperparathyroidism (PHPT) and to investigate the relationship between zonulin, calcium, and parathormone (PTH) levels. Methods The study included 34 healthy control (HC) and 39 patients with PHPT. Serum calcium, phosphorus, magnesium,...
Mon Sep 28, 2020 03:00
Abstract Purpose Almost two-thirds of the population undergoing bariatric surgery (BS) suffers from obstructive sleep apnea (OSA). Continuous positive airway pressure (CPAP) is the standard treatment for moderate to severe OSA and is recommended in patients undergoing BS perioperatively. A severe and dreaded complication after BS is anastomotic leakage. There is theoretical concern that perioperative CPAP use may result in increased...
Mon Sep 28, 2020 03:00
This is the first study to show that the gene advillin is expressed in a specific population of enteric neurons known as intrinsic primary afferent neurons (IPANs), which uniquely endow the digestive system with intrinsic neural reflex activity. The identity of advillin as a marker for IPANs is supported by morphological, neurochemical, and physiological evidence. Abstract Background The gut is the only organ system with intrinsic neural reflexes. Intrinsic primary afferent neurons (IPANs)...
Mon Sep 28, 2020 16:57
Abstract Objectives The global pandemic COVID‐19 has resulted in significant global morbidity, mortality and increased healthcare demands. There is now emerging evidence in of patients experiencing urticaria. We sought to systematically review current evidence, critique the literature and present out findings. Methods Allowing PRISMA guidelines, a comprehensive literature search was carried out with Medline, EMBASE, Scopus, Cochrane, and Google Scholar, using key MeSH words, which include...
Mon Sep 28, 2020 16:46
In estimating the number gibbon groups by acoustic means, we must account for the fact that groups farther away have a lower probability of being heard. Shown here are two models for the probability of detection of gibbon groups at increasing distance from the sample point, fit to the actual data (histograms) on gibbon groups heard. Abstract Effective conservation demands more accurate and reliable methods of survey and monitoring of populations. Surveys of gibbon populations have relied mostly...
Mon Sep 28, 2020 18:47
Two groups of tiny, delicate marine organisms, sea butterflies and sea angels, were found to be surprisingly resilient -- having survived dramatic global climate change and Earth's most recent mass extinction event 66 million years ago.
Mon Sep 28, 2020 16:37
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