Reconstruction of human oncological tracheal defects with xenogenic acellular dermal matrix

Publication date: Available online 24 April 2016
Source:Auris Nasus Larynx
Author(s): Ping Li, Shisheng Li, Qinglai Tang, Xiangbo He, Danhui Yin, Shuang Wang, Xinming Yang
ObjectiveThis study aimed to explore the effectiveness of xenogenic acellular dermal matrix (xeno-ADM) in tracheal reconstruction.MethodTwo patients were treated with this surgical method to reconstruct the trachea in 2013. The patients were diagnosed with tracheal adenoid cystic carcinoma by histopathological biopsy. The tumor was resected with half of the tracheal circumference and repaired by xeno-ADM. The patients were followed up for 31 and 33 months, respectively.ResultNo infection or tracheal fistula was observed. The grafts were clear. Both patients were successfully decannulated without dyspnea and could breathe and speak without prosthesis. The cervical mobility was not impaired.ConclusionXeno-ADM was successfully used to reconstruct a stable and well-functioning trachea. This surgical method is simple, safe, and effective with fewer complications.



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