Eosinophils and mast cells: a lineage apart

Nature Immunology 17, 609 (2016). doi:10.1038/ni.3446

Authors: Sandrine Sarrazin & Michael H Sieweke

Single-cell transcriptome analysis has identified progenitor populations with mast-cell and eosinophil potential that are distinct from the neutrophil-monocyte lineage, segregate early in hematopoietic development and can be discriminated by expression of the transcription factor GATA-1.

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