Intracranial translucency as a sonographic marker for detecting open spina bifida at 11-13+6 weeks scan: Our experience.

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Intracranial translucency as a sonographic marker for detecting open spina bifida at 11-13+6 weeks scan: Our experience.

Indian J Radiol Imaging. 2017 Oct-Dec;27(4):427-431

Authors: Teegala ML, Vinayak DG

Abstract
Aims and Objectives: The fourth ventricle, seen as intracranial translucency (IT) at 11-13+6 weeks, has been reported to be obliterated in cases of open spina bifida (OSB). Our aim was to assess its role in detecting OSB at 11-13+6 weeks.
Materials and Methods: This prospective study was conducted at foetal medicine unit from January 2014 to June 2015. All women who underwent both first and mid-trimester scan in our unit were included in the study. IT was categorized as normal, obliterated or not clear. Spine was examined during both scans.
Results: Totally, 341 cases were included in the study. IT was found to be obliterated in four cases and not clear in one case. There was demonstrable OSB at 11-13+6 weeks in two cases, at 15-16 weeks in two cases and at 24 weeks in one case. In the remaining 336 cases with normal IT, spine was found to be normal at target scan.
Conclusion: Mid-sagittal view of face that is routinely used to measure nuchal translucency (NT) can also be used to detect OSB. It is feasible to integrate IT into the routine 11-13+6 weeks scan.

PMID: 29379237 [PubMed]

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