Σάββατο 20 Ιανουαρίου 2018

The DNA copy number landscape of a collision tumor.

The DNA copy number landscape of a collision tumor.

Clin Neuropathol. 2018 Jan 19;:

Authors: Kearney H, Cryan JB, Looby S, Brett FM, Farrell MA, Buckley PG

Abstract
Intracranial collision tumors are composed of two histologically distinct but merging components, and are rare. Their genetic profile has rarely been described. Comparative genome hybridization of a combined meningioma and oligodendroglioma demonstrated deletion of chromosome 22q and of 19q in both tumors. Somatic deletion of chromosome 22q and 19q is associated with development of an intracranial collision tumor.
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PMID: 29350171 [PubMed - as supplied by publisher]



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