Deceptive nasal NK/T-cell lymphoma.

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Deceptive nasal NK/T-cell lymphoma.

Trop Doct. 2017 Jul;47(3):268-271

Authors: Thakur JS, Mahajan A, Saluja M, Mohindroo NK

Abstract
Nasal NK/T cell lymphoma is rare and it easily masquerades as chronic rhinosinusitis. It has a very poor prognosis and hence early diagnosis, although difficult, is necessary for better outcome. We present a case of a 30-year-old man who presented with nasal obstruction, facial oedema and crusts. High-resolution computed tomography found soft tissue in all sinuses and the nasal cavity. Endoscopic biopsy revealed necrotic and inflammatory tissue with fungi on culture. A diagnosis of fungal rhinosinusitis was made but the patient did not respond to antifungal drugs. A histopathology review with immunohistochemistry suggested nasal NK/T cell lymphoma. The patient was started on chemotherapy but died within 1 week.

PMID: 28689491 [PubMed - indexed for MEDLINE]

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