The analysis of scalp irritation by coacervates produced in hair shampoo via FTIR with Focal Plane Array detector, X-ray photoelectron microscopy and HaCaT cells

Abstract

Objective

Coacervates are inevitably formed on scalp on using hair washing products. Our goal was to analyze the coacervates in detail to identify the part responsible for scalp stimulation.

Methods

Shampoo that increases coacervate formation was applied to in-vitro skin and was washed. The residue was then analyzed using Fourier-transform infrared spectroscopy–focal plane array (FTIR-FPA), and X-ray photoelectron microscopy (XPS). And HaCaT cells were used for irritant test of coacervate.

Results

Through this research, it was confirmed that the coacervate was a macromolecule structurally similar to a cationic polymer and contains an anionic surfactant. Its anionic surfactant was structurally semi-stable so that it released onto scalp when it absorbs moi8sture.

Conclusion

Coacervate releases sulfate bonding into the matrix when it is exposed to water. Thus, the scalp stimulation would be expected.

This article is protected by copyright. All rights reserved.

from #ENT via xlomafota13 on Inoreader http://ift.tt/2aIOsxO
via IFTTT