Mendelian randomization analysis demonstrates that low vitamin D is unlikely causative for pediatric asthma.

Publication date: Available online 20 August 2016
Source:Journal of Allergy and Clinical Immunology
Author(s): Erik B. Hysinger, Jeffrey D. Roizen, Frank D. Mentch, Lyam Vazquez, John J. Connolly, Jonathan P. Bradfield, Berta Almoguera, Patrick M. Sleiman, Julian L. Allen, Michael A. Levine, Hakon Hakonarson

Teaser

We confirmed associations between 25(OH)D and asthma in our cross-sectional cohort; however, genetically predicted vitamin D status was not associated with asthma. These results suggest that vitamin D is unlikely causative for pediatric asthma.


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