Τετάρτη 8 Ιουνίου 2016

Toxic epidermal necrolysis: The past, the guidelines and challenges for the future

Toxic epidermal necrolysis (TEN) is one of the most extraordinary diseases that dermatologists face in terms of morbidity, mortality and sequelae. It has also been a major challenge for research to elucidate its mechanisms. It is more than an acute skin failure; it is a systemic disease that requires a multidisciplinary approach. This challenge has been taken up and resulted in collaboration between dermatologists, plastic surgeons, burn surgeons, intensivists and other specialists. Indeed, during the past decade, major advances have been made in diagnosing Stevens-Johnson syndrome (SJS) and TEN, managing their manifestations and identifying both their pathogenesis and at-risk populations.

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