Objectives: To assess the impact of tobacco smoking on outcomes after ossiculoplasty. Study Design: Case series with chart review. Setting: Tertiary care center. Patients: Adult patients (16-88 yr of age) undergoing ossiculoplasty with cartilage tympanoplasty. Outcome Measures: Patients were classified as smokers (TOB+) or nonsmokers (TOBN). Comparisons were then made between these two groups with regard to early and late audiometric outcomes, rate of cure of conductive hearing loss, rate of successful graft healing, and incidence of complications after surgery. Results: There was no significant difference between the two groups with regard to postoperative [DELTA]PTA-ABG (change in pure-tone average air-bone gap) (-14.4 dB vs. -14.6 dB for TOBN vs. TOB+, respectively, p = 0.946) or final audiometric outcome ([DELTA]PTA-ABGfinal) (-13.6 dB vs. -11.7 dB for TOBN vs. TOB+, respectively, p = 0.315), cure of conductive hearing loss, defined as closure of the PTA-ABG to
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