Personalized medicine. Closing the gap between knowledge and clinical practice

Publication date: Available online 11 June 2016
Source:Autoimmunity Reviews
Author(s): Juan-Manuel Anaya, Carolina Duarte-Rey, Juan C. Sarmiento-Monroy, David Bardey, John Castiblanco, Adriana Rojas-Villarraga
Personalized medicine encompasses a broad and evolving field informed by a patient distinctive information and biomarkers profile. Although terminology is evolving and some semantic interpretations exist (e.g., personalized, individualized, precision), in a broad sense personalized medicine can be coined as: "To practice medicine as it once used to be in the past using the current biotechnological tools." A humanized approach to personalized medicine would offer the possibility of exploiting systems biology and its concept of P5 medicine, were predictive factors for developing a disease should be examined within populations in order to establish preventive measures on at-risk individuals, for whom healthcare should be personalized and participatory. Herein, the process of personalized medicine is presented together with the options that can be offered in health care systems with limited resources for diseases like rheumatoid arthritis and type 1 diabetes.



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