Bach2 is required for B cell and T cell memory differentiation

Nature Immunology 17, 744 (2016). doi:10.1038/ni.3493

Authors: Tom Sidwell & Axel Kallies

B cell and T cell memory differentiation requires the transcription factor Bach2, which inhibits the effector-cell fate by limiting antigen-receptor-stimulation-induced gene expression and restricting premature expression of the transcriptional regulator Blimp-1.

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