Use of a purified collagen membrane to aid closure of palatal fistulae

Publication date: Available online 2 March 2016
Source:Journal of Plastic, Reconstructive & Aesthetic Surgery
Author(s): Duncan D. Atherton, John G. Boorman
IntroductionFistula formation remains a difficult clinical problem following closure of palatal clefts. There is also a significant recurrence rate after attempted closure. We present our results of fistula closure augmented with Bio-Gide®; a purified porcine collagen membrane designed to promote guided tissue regeneration.MethodsWe reviewed the records of 263 patients operated on between 1993 and 2011 who had closure of a palatal fistula. This included 61 who had closure augmented with Bio-Gide and 202 patients who had fistulae closure by other techniques without its use.We reviewed the age at surgery; sex; location of fistula; cleft type and outcome.Operation success was defined as an asymptomatic patient along with visible confirmation of closure of the fistula.ResultsThe overall fistula closure rate was 75% in the Bio-Gide group and 63% in the non-Bio-Gide group (p=0.070) and in the UCLP patients 86% vs. 61% (p=0.027)DiscussionBio-Gide has improved the success rate in fistula closure in this study. Using this technique, fistula closure can be performed as a day case procedure, does not need to transgress any original suture lines and additionally has the advantage of not requiring the harvesting of any autologous tissue to augment the repair.



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