The role of the mean platelet volume and neutrophil-to-lymphocyte ratio in peritonsillar abscesses

Publication date: Available online 28 March 2016
Source:Brazilian Journal of Otorhinolaryngology
Author(s): Mehmet Şentürk, İsa Azgın, Gültekin Övet, Necat Alataş, Betül Ağırgöl, Esra Yılmaz
IntroductionPeritonsillar abscess (PTA) is a serious infectious disease of the tonsillar tissue. Treatment generally requires both medical and surgical approaches to relieve the symptoms. Recently, in addition to clinical follow-up, some inflammatory markers, such as the mean platelet volume (MPV) and neutrophil-to-lymphocyte ratio (NLR), have been considered to be additional inflammatory monitoring markers in inflammatory diseases.ObjectiveThe aim of this study was to describe the role of MPV and NLR in patients with PTA.MethodsA retrospective study was conducted in 88 patients with PTA and 88 healthy individuals. We analyzed the white blood cell (WBC) count, neutrophil count, lymphocyte count, platelet count, C-reactive protein (CRP), MPV and NLR values and compared them among the patient and control groups.ResultsThe MPV levels were significantly higher in the PTA pretreatment group than in the PTA posttreatment group and the control group. An MPV value of 8.7 was the optimal cut-off value for evaluating the sensitivity, specificity, positive predictive value and negative predictive value of 75%, 65.9%, 68% and 72%, respectively. The NLR levels were significantly higher in the PTA pretreatment group than in the PTA post-treatment group and the control group. An NLR value of 3.08 was the optimal cut-off value for evaluating the sensitivity, specificity, positive predictive value and negative predictive value of 90.9%, 90.9%, 90.9% and 90.9%, respectively. While the WBC count, neutrophil count, lymphocyte count and CRP values were significantly different among the patient and control groups (p<0.05), the platelet count was not significantly different among the patient and control groups (p>0.05).ConclusionThe MPV and NLR values made us think that these parameters were quick, inexpensive and reliable inflammatory follow-up parameters and could be easily integrated into daily practice for PTA treatment except platelet count.



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