The relationship between esophageal cancer, chagasic megaesophagus and HPV: myths, tales or reality?

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The relationship between esophageal cancer, chagasic megaesophagus and HPV: myths, tales or reality?

Histol Histopathol. 2018 Apr 24;:11993

Authors: Munari FF, Carloni AC, Mariano VS, Syrjanen K, Reis RM, Longatto-Filho A

Abstract
A supposed role for persistent high-risk human papillomavirus (HPV) infection in esophageal squamous cell carcinoma (ESCC) etiology has been suggested by a number of studies. Concomitantly, megaesophagus induced by the Trypanosoma cruzi cell-cycle activity also shows a potential association with ESCC. This review discusses esophageal cancer and the potential association between chagasic megaesophagus and HPV as risk factors for ESCC development.

PMID: 29687834 [PubMed - as supplied by publisher]

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