[Rectal diffuse large B cell lymphoma appearing after immunosuppression for ulcerative colitis. Report of one case].

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[Rectal diffuse large B cell lymphoma appearing after immunosuppression for ulcerative colitis. Report of one case].

Rev Med Chil. 2017 Oct;145(10):1342-1348

Authors: Quera R, Flores L, Simian D, Kronberg U, Vial MT, de Guevara DL, García-Rodríguez MJ

Abstract
Primary colorectal lymphoma is a rare form of presentation of gastrointestinal tract lymphomas. Inflammatory bowel disease and its treatment are risk factors for its development. We report a 47-year-old male patient with Ulcerative Colitis of two years of evolution, treated initially with azathioprine and later on with infliximab. Due to a relapse in symptoms after the second dose of infliximab, a new coloncoscopy was performed showing a rectal ulcerative lesion, corresponding to a large cell Non-Hodgkin's Lymphoma. The patient was successfully treated with RCHOP chemotherapy (Rituximab cyclophosphamide doxorubicin vincristine prednisone). He is currently in disease remission.

PMID: 29488576 [PubMed - indexed for MEDLINE]

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