Restrictive interleukin-10 induction by an innocuous Parainfluenza virus vector ameliorates nasal allergy

Publication date: Available online 16 July 2016
Source:Journal of Allergy and Clinical Immunology
Author(s): Keiichi Yamanaka, Takehisa Nakanishi, Kana Isono, Chisami Hasegawa, Hiroyasu Inada, Kento Mizutani, Yoshiaki Matsushima, Karin Okada, Tomotaka Mabuchi, Makoto Kondo, Akisa Yamagiwa, Masato Kakeda, Koji Habe, Tetsuya Nosaka M, Esteban C. Gabazza, Hidetoshi Yamazaki, Hitoshi Mizutani, Mitsuo Kawano

Teaser

A novel therapy: Topical interleukin-10 application via non-replicating human Parainfluenza type 2 virus vector ameliorates mouse cedar pollinosis without affecting other lymphoid tissue.


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