A randomized trial of quilizumab in adults with refractory chronic spontaneous urticaria

Publication date: Available online 19 July 2016
Source:Journal of Allergy and Clinical Immunology
Author(s): Jeffrey M. Harris, Christopher R. Cabanski, Heleen Scheerens, Divya Samineni, Mary S. Bradley, Colette Cochran, Petra Staubach, Martin Metz, Gordon Sussman, Marcus Maurer

Teaser

Targeting IgE-switched and memory B cells in CSU via quilizumab treatment did not provide clinically meaningful benefit, indicating that IgE class switching or IgE memory is not a key driver of CSU pathogenesis.


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