Hearing impairment in children with permanent congenital hypothyroidism: Data from Northwest India

Devi Dayal, Nirmal Hansdak, Dharam Vir, Atul Gupta, Jaimanti Bakshi

Thyroid Research and Practice 2016 13(2):67-70

Background: There is an increased risk of hearing impairment in permanent congenital hypothyroidism (CH). Only a few studies have explored the prevalence of hearing impairment in CH and their results vary widely. There is no data on hearing impairment in Indian children with CH. Setting and Design: Pediatric Endocrinology Clinic of a large tertiary care hospital located in Northwest India. Cross sectional study. Materials and Methods: Hearing evaluation of 77 children diagnosed with permanent CH was performed with a battery of tools that included Middle ear analysis, Pure Tone Audiometry (PTA), Behavioral Observation Audiometry (BOA) and Oto Acoustic Emissions (OAE). The choice of assessment tool was based on patient's age. Results: The mean age at diagnosis and at inclusion into the study was 3.0±2.7 years and 5.2±3.3 years respectively. The majority (63, 82%) of patients had symptoms suggestive of hypothyroidism; none complained of hearing loss. The etiological diagnosis was thyroid agenesis in 55 (71.4%), ectopia in 5 (6.5%), dyshormonogenesis in 9 (11.7%) and hypothyroidism with eutopic gland in 8 (10.3%) patients. Middle ear analysis, PTA, BOA and OAE was done in 48, 44, 43 and 53 patients respectively. Sensorineural hearing loss was detected in 1 out of 77 (1.2%) patients while conductive hearing loss was found in 5 (6.5%) patients. Conclusion: Hearing loss was present in a small proportion of patients with permanent CH. Further larger studies are required to determine the exact prevalence of hearing impairment in Indian children with permanent CH.

from #ENT via xlomafota13 on Inoreader http://ift.tt/1ROVlrN
via IFTTT