Changes in the salivary microbiota of oral leukoplakia and oral cancer

Oral cancer is one of the most prevalent cancers in the world, with oral squamous cell carcinoma (OSCC) accounting for 90% of all oral cancers [1]. The oral cavity is the second microbiome habitat in the human body and harbors numerous microbiota; an estimated 500–700 bacteria belonging to different species are present here [2]. To better understand the relationship between the salivary microbiota and oral leukoplakia (OLK) and OSCC, we evaluated changes in the salivary microbiota of patients with OSCC and OLK relative to the oral bacterial profiles in healthy controls (HCs) in present study.

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