Δευτέρα 29 Φεβρουαρίου 2016

Usefulness of rhinomanometry in the identification and treatment of patients with obstructive sleep apnoea: an algorithm for predicting the relationship between nasal resistance and continuous positive airway pressure. A retrospective study

Abstract

Objectives

We try to assess the relationship between nasal resistance measured by rhinomanometry and the pressure used in CPAP.

Design

Retrospective medical case series review, January 2004 to December 2014.

Setting

Tertiary care academic medical center.

Participants

38 patients (m=56.55 years; male=90.5%) with CPAP settings ≤8 and 39 patients (m=57.49 years; male=74.9%) with pressure settings ≥12.

Main outcome measures

Study variables were BMI, neck circumference, Epworth Sleepiness Scale score, nasopharyngeal examination and computerized anterior active rhinomanometry, sitting and supine, in basal conditions and after intranasal administration of oxymetazoline (0.05%). Nocturnal polysomnography was performed to calculate the apnoea-hypopnoea index without and with CPAP to analysis the effectiveness of the treatment.

Results

BMI and resistance in supine position after vasoconstriction at 150 Pa were useful variables to predict the pressure setting that should be used. We obtained an equation to calculate the probability that a patient requires a pressure greater than 12 cm H2O as a function of their BMI and total nasal airflow at 150 Pascal in supine position after vasoconstriction.

Conclusions

Rhinomanometry is useful to predict the impact of structural nasal modifications on the positive pressure to support decision-making in relation to surgery.

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