The Itch to degrade ROR-γt

Nature Immunology 17, 898 (2016). doi:10.1038/ni.3516

Authors: Sascha Rutz & Wenjun Ouyang

The E3 ubiquitin ligase Itch limits interleukin 17A (IL-17A)-mediated intestinal inflammation by targeting the transcription factor ROR-γt for proteasomal degradation.

from #ENT via xlomafota13 on Inoreader http://ift.tt/29VZkZO
via IFTTT