Sino-Nasal Outcome Test-22 quality of life patterns in patients presenting with nasal septal perforation.

Sino-Nasal Outcome Test-22 quality of life patterns in patients presenting with nasal septal perforation.

Clin Otolaryngol. 2017 Nov 11;:

Authors: Leong SC, Webb CJ

Abstract
OBJECTIVES: To assess the impact of nasal septal perforation on quality of life.
DESIGN: Retrospective cohort study.
SETTING: Rhinology clinics from two hospitals in Liverpool, United Kingdom.
PARTICIPANTS: Patients diagnosed with nasal septal perforation (NSP).
MAIN OUTCOME MEASURES: Patients (n=26) diagnosed with NSP completed the Sino-Nasal Outcome Test-22 (SNOT-22). The collated data was compared with SNOT-22 scores from a cohort of healthy volunteers (n=34) and a cohort of patients (n=30) diagnosed with chronic rhinosinusitis (CRS).
RESULTS: The mean total SNOT-22 score of NSP and CRS cohorts were higher than that observed in healthy volunteers. The mean total SNOT-22 score in the CRS cohort (57.2, standard deviation SD 10.3) was the higher than NSP (50.2, SD 23.5), although this difference did not achieve statistical significance. The mean score for the rhinologic-specific domains (rhinologic symptoms, extra-nasal rhinologic symptoms), ear/facial symptoms and psychological dysfunction domain were higher in the CRS cohort compared to NSP, although statistical significance was only observed in the extranasal rhinologic symptoms domain (11.2, SD 2.4 vs. 6.4, SD 4.1). Conversely, the mean sleep dysfunction domain score for NSP (12.7, SD 7.5) was higher than CRS (10.0, SD 4.9 respectively) although this was not statistically significant.
CONCLUSIONS: The present study has assessed the clinimetric and psychometric properties of patients suffering with symptomatic NSP. Future reports should consider inclusion of SNOT-22 data but with the addition of perforation-specific symptoms (nasal crusting, epistaxis, whistling noise). This article is protected by copyright. All rights reserved.

PMID: 29130649 [PubMed - as supplied by publisher]

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